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PEPTIDE FUSION

A peptide face cream formulated to firm skin by day and support its natural renewal overnight

TERMS OF USE

Membership subscription

By selecting "Subscribe & Save" option, you agree to receive a shipment of Pureance Peptide Fusion each month. You are authorizing us to charge your credit card monthly, matching the package you have selected. Coupon or discount codes can only be applied to initial purchases and such discounts do not apply to future autoship products. You can stop shipments at any time in your customer account or by calling our customer support team toll free at (800) 595-0735, Mon - Sun 24/7, Outside the US, call us at +1-703-740-4444. All terms & conditions apply.

Recurring Billing Terms of Service

Once your initial order is shipped, you will be billed for and shipped a new order of Pureance Peptide Fusion corresponding with your membership subscription plan:

  • Billed every month - 1 Bottle of Pureance Peptide Fusion;
  • Billed every month - 2 Bottles of Pureance Peptide Fusion;
  • Billed every month - 3 Bottles of Pureance Peptide Fusion.

Your purchase will appear on your bank statement under the name "Pureance, LLC".

Membership Plan Options

3-Bottles Plan

  • 3 Bottles of Pureance Peptide Fusion
  • $113.40 billed monthly

2-Bottles Plan

  • 2 Bottles of Pureance Peptide Fusion
  • $81.00 billed monthly

1-Bottle Plan

  • 1 Bottle of Pureance Peptide Fusion
  • $44.10 billed monthly

There is no purchase minimum or commitment to purchase. To customize this program to meet your needs, to update billing info, or to inquire about future shipments and charges, call customer service anytime toll free at (800) 595-0735, Outside the US, call us at +1-703-740-4444. Please note exact shipment times may vary. Every Peptide Fusion order is covered by our 365-day Customer Satisfaction Guarantee.

Important Notice

This membership ensures that depending on your chosen subscription plan, you'll receive an order of Pureance Peptide Fusion every (30) thirty days until you choose to end your membership and stop receiving our product as well as exclusive, members-only content. Memberships are continuous and are automatically renewed unless you terminate your subscription. You are free to cancel your subscription at any time without penalty or early cancellation fees. Manage your subscription in your Pureance account. Send an email to support@pureance.com or call us toll free at (800) 595-0735, Mon – Sun 24/7, Outside the US, call us at +1-703-740-4444.

When you enroll in the Pureance Monthly Subscription, you acknowledge you will be billed for and receive your order of Pureance Peptide Fusion every (30) thirty days depending on your subscription plan. The credit card or debit card you used to enroll in this exclusive membership will be billed every subscription cycle. Coupon or discount codes can only be applied to initial purchases and such discounts do not apply to future autoship products.

You acknowledge and agree that these services are provided on a membership subscription basis and that you will be charged recurring membership fee depending on your original date of purchase and your chosen subscription plan.

You expressly authorize Pureance to charge your credit card or debit card every (30) thirty days depending on your chosen subscription and you disclaim any responsibility or liability for any overdraft charges or fee you may incur from your card issuer or bank for insufficient funds or any other associated fees related to monthly repeat billing. You acknowledge and agree that we will not obtain additional authorization from you for each monthly membership charge.

Confirmation of Consent will be sent to you via email notifying you of your subscription and terms.

Vitality Club Membership
Terms of Use

MEMBERSHIP SUBSCRIPTION

Recurring Billing Terms of Service

Upon enrollment, you will be charged $0 for a one (1) week trial membership. No payment will be processed during the trial period.

After the trial ends, you will be charged $77 per month for a period of six (6) months, with payments automatically billed in recurring thirty (30) day intervals.

Upon completion of the six (6) month billing period, you will be granted lifetime access to Vitality Club at no additional cost. No further charges will be incurred beyond this point.

Your purchase will appear on your bank statement under the name PUREANCE 8005950735.

Membership Pathway

1-week trial for $0

  • Start with a 1-week free trial (one-time, non-renewable).

6-month billing period for $77/month

  • To continue, you will be automatically upgraded to a 6-month billing period for $77 per month, billed every 30 days.

Lifetime access

  • After completing the 6-month billing period, you automatically unlock lifetime access at no additional cost.

For questions regarding your membership, billing information, or account access, please call customer service anytime toll free at toll free at (800) 595-0735, outside the US, call us at +1-703-740-4444.

Important Notice

By leaving the Vitality Club item in your cart, you agree to get access and subscription to a digital Vitality Club membership.

Unless you cancel your membership before the end of the free-trial period, you authorize us to automatically charge your credit card $77 per month for 6 months as part of a recurring subscription. The subscription will renew automatically each month during this six-month period unless canceled in accordance with these Terms. Coupon or discount codes can only be applied to initial purchases and such discounts do not apply to future autoship products.

After the completion of the 6 monthly payments, you will receive lifetime access to the Vitality Club digital membership with no additional cost.

You may cancel your subscription at any time prior to completion of the 6 monthly payments in your customer account or by calling our customer support team toll free at (800) 595-0735, Mon - Sun 24/7, outside the US, call us at +1-703-740-4444.

If you cancel within thirty (30) days of being charged, you may request a refund for that month’s payment. Refund requests submitted after the thirty (30) day period from the date of the applicable charge will not be accepted, and no refund will be due.

You acknowledge and agree that these services are provided on a membership subscription basis and that you will be charged the recurring membership fee depending on your original date of purchase, in accordance with the terms of the subscription program.

You expressly authorize Vitality Club to charge your credit card or debit card every (30) thirty days for (6) six months, in accordance with your subscription plan and you disclaim any responsibility or liability for any overdraft charges or fee you may incur from your card issuer or bank for insufficient funds or any other associated fees related to monthly repeat billing. You acknowledge and agree that we will not obtain additional authorization from you for each monthly membership charge.

Confirmation of Consent will be sent to you via email notifying you of your subscription and terms.

Restrictions Regarding Resale

Products purchased by consumers from Company are for personal use only and may not be resold in any fashion either online or in brick-and-mortar stores. This restriction specifically includes a prohibition on the sale of products on any digital marketplace.

Contacting Us

If you have any questions about these Terms Of Use, Privacy Policy, the practices of our sites, or your dealings with our sites, you may contact:

Customer Support Team
Pureance
(800) 595-0735, Mon - Sun 24/7, Outside the US, call us at +1-703-740-4444
support@pureance.com

POPULAR CHOICE

Subscribe & Save

$37.8/Bottle

$69

You save $93.6

  • Vitality Club 7 days free trial
  • No commitment, pause or cancel anytime
  • 365 day money back guarantee
  • FREE monthly delivery in US
  • Terms and Conditions

One Time Purchase

$42/Bottle

$69

You save: $81

Choose your package:

365 day guarantee
ecocert cosmos natural
scientifically backed
In Stock
Vitality club

Vitality Club:
Your Complete Wellness Partner

Vitality club
  • You've already chosen quality Pureance supplements, hair care, or skincare products – now get the most out of them with expert guidance tailored just for you. Get exclusive access to health experts, nutritionist-approved recipes, targeted workouts, and science-backed health tools that work together with your Pureance routine.
  • Experience faster results and real transformation. Our strategies could help you get more from every product, so you could reach your health goals with confidence.
  • Try it FREE and see the difference for yourself! As a Vitality Club subscriber, you'll continue to receive ongoing expert support and exclusive content. Not for you? Simply contact our customer support team to cancel anytime.
  • By placing the order, I understand and agree that my cart includes a digital “Vitality Club” membership with a 7-day free trial. Unless canceled before the trial ends, I agree and authorise Pureance to automatically charge my credit card $77 per month for a total of 6 consecutive monthly payments. Upon completion of these payments, I will receive lifetime access to the “Vitality Club” digital membership. I can cancel my membership at any time through my account or by contacting support team toll-free at (800) 595-0735 (Mon–Sun, 24/7). Outside the U.S., call +1-703-740-4444. All terms & conditions apply

A PEPTIDE FACE CREAM WORTH TALKING ABOUT

Peptide Fusion is for anyone who’s noticed their skin starting to lose that quiet, snapped-back resilience it used to have – a few more fine lines than before, a little less bounce than you remember. At its center is Hexapeptide-11, a biomimetic peptide studied for its ability to help activate skin cells’ own antioxidant response and support natural rejuvenation. By day, this lightweight cream maintains firmness, by night, it promotes skin’s own renewal process. Hydrolyzed hyaluronic acid and Ginkgo Biloba round it out, quietly hydrating and guarding against everyday oxidative stress.

  • Helps firm the look of skin by day
  • Supports skin’s natural rejuvenation process overnight
  • Targets the appearance of fine lines with consistent use
  • Promotes lasting hydration, morning and night
  • Simplifies your routine – one lightweight cream, applied twice a day

Safe for: all skin types.

Woman resting beside Pureance Peptide Fusion peptide face cream Woman resting beside Pureance Peptide Fusion peptide face cream Woman resting beside Pureance Peptide Fusion peptide face cream

GENTLE & EFFECTIVE

Peptide Fusion is formulated to feel weightless on skin while still delivering real, peptide-driven support. It absorbs quickly, layers easily under makeup or SPF, and leaves no greasy residue behind – gentle enough for daily use, without asking you to compromise on results.

Vegan

Vegan

Paraben Free

Paraben Free

Sulfate Free

Sulfate Free

Ecocert COSMOS Certified

Ecocert COSMOS Certified

Clean Natural Ingredients

Clean Natural Ingredients

KEY INGREDIENTS

Hexapeptide-11

Hexapeptide-11

A biomimetic peptide originally isolated from yeast, Hexapeptide-11 has been studied for its ability to help activate the skin’s own antioxidant response and the cellular processes involved in rejuvenation, rather than just sitting on the surface. In laboratory research, it was shown to help promote cellular renewal and may help support skin cells facing oxidative stress. In a four-week study, it was associated with a measurable improvement in skin’s elasticity – early evidence, but a real signal this peptide is doing more than moisturizing.

Hydrolyzed Hyaluronic Acid & Sodium Hyaluronate

Hydrolyzed Hyaluronic Acid & Sodium Hyaluronate

Two forms of hyaluronic acid, working at different depths: the smaller, hydrolyzed form may help reach deeper into skin, while sodium hyaluronate hydrates closer to the surface – together, giving skin moisture from the inside out. Clinical research has linked it to improved elasticity, better hydration and softer-looking wrinkles.

Ginkgo Biloba Leaf Extract

Ginkgo Biloba Leaf Extract

Rich in antioxidant flavonoids, Ginkgo Biloba has been studied for its ability to help support skin cells from oxidative stress – the everyday damage that could leave skin looking tired and less resilient. A cosmeceutical trial with human volunteers supports its use in formulations like this one, working to keep skin looking calmer and more balanced over time.

Hexapeptide-11 Hexapeptide-11

Hexapeptide-11

A biomimetic peptide originally isolated from yeast, Hexapeptide-11 has been studied for its ability to help activate the skin’s own antioxidant response and the cellular processes involved in rejuvenation, rather than just sitting on the surface. In laboratory research, it was shown to help promote cellular renewal and may help support skin cells facing oxidative stress. In a four-week study, it was associated with a measurable improvement in skin’s elasticity – early evidence, but a real signal this peptide is doing more than moisturizing.

Hydrolyzed Hyaluronic Acid & Sodium Hyaluronate Hydrolyzed Hyaluronic Acid & Sodium Hyaluronate

Hydrolyzed Hyaluronic Acid & Sodium Hyaluronate

Two forms of hyaluronic acid, working at different depths: the smaller, hydrolyzed form may help reach deeper into skin, while sodium hyaluronate hydrates closer to the surface – together, giving skin moisture from the inside out. Clinical research has linked it to improved elasticity, better hydration and softer-looking wrinkles.

Ginkgo Biloba Leaf Extract Ginkgo Biloba Leaf Extract

Ginkgo Biloba Leaf Extract

Rich in antioxidant flavonoids, Ginkgo Biloba has been studied for its ability to help support skin cells from oxidative stress – the everyday damage that could leave skin looking tired and less resilient. A cosmeceutical trial with human volunteers supports its use in formulations like this one, working to keep skin looking calmer and more balanced over time.

THE DIFFERENCE CONSISTENCY MAKES

Close-up of dry skin texture without Peptide Fusion Close-up of dry skin texture without Peptide Fusion Close-up of dry skin texture without Peptide Fusion

WITHOUT PEPTIDE FUSION

Not every wrinkle-targeting cream with peptides addresses what’s actually happening underneath. Skin renews itself on a cycle – in youth, the epidermis fully turns over roughly every 40 to 56 days. That renewal depends on a cellular quality-control system called proteostasis, which clears damaged proteins and keeps skin cells functioning properly. Proteostasis decline is recognized as one of the core mechanisms behind aging, and it could begin before any visible signs show up. In simple terms, this means skin cells gradually lose some of their own ability to defend against stress and repair themselves, which shows up over time as fine lines and skin that feels less resilient.

Firmer skin texture after using Pureance peptide cream Firmer skin texture after using Pureance peptide cream Firmer skin texture after using Pureance peptide cream

WITH PEPTIDE FUSION

Peptide Fusion is formulated around Hexapeptide-11, a biomimetic peptide studied in laboratory research for its ability to help promote the very systems that decline with age – including the antioxidant response and the proteasome, autophagy and chaperone pathways that make up skin’s proteostasis network. In a four-week study of this ingredient, that activation was associated with a measurable improvement in skin elasticity. It’s this kind of ingredient-level research that shaped this formula, designed to work with skin’s own biology rather than just sit on top of it.

ADDRESSING YOUR SKIN'S CRITICAL NEEDS

As skin ages, it faces three primary challenges:

Loss of Resilience:

Skin cells’ natural antioxidant and renewal pathways could become less active over time, leaving skin looking less firm and slower to bounce back.

image

Oxidative Stress:

Everyday environmental stressors accelerate the breakdown of the very pathways that keep skin looking resilient, compounding visible signs of aging year after year.

image

Fine Lines & Wrinkles:

As skin’s structural support declines, expression lines that once relaxed on their own could start to settle in and become more visible over time.

image

Peptide Fusion helps address all three concerns at once with its peptide-and-antioxidant formula, making it one of the more complete peptide creams for face care built for skin that needs more than surface-level hydration.

NOT ALL FACE CREAMS ARE CREATED EQUAL

Peptide Fusion is formulated to a professional standard – Ecocert COSMOS Natural certified, and built around a peptide studied for its ability to promote skin’s own renewal, not just sit on top of it.

Comparison table showing Peptide Fusion vs generic face creams Comparison table showing Peptide Fusion vs generic face creams Comparison table showing Peptide Fusion vs generic face creams
PUREANCE HAS BEEN
FEATURED ON:
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Pureance is not endorsed by, sponsored by, or affiliated with any of these organizations.
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Frequently Asked Questions About Peptide Fusion

How Does Peptide Fusion Work On My Skin?

Peptide Fusion is built around Hexapeptide-11, a peptide studied for its ability to help activate skin cells' own antioxidant and rejuvenation pathways rather than working only on the surface. This peptide formula is designed to help support the look of firmness, hydration and resilience with consistent daily use – the reason many people looking for the best peptide face cream land here.

Is Peptide Fusion Safe For Sensitive Skin?

Yes. Peptide Fusion is formulated to be gentle and hypoallergenic, and is paraben-free, sulfate-free and silicone-free. As with any new skincare product, we recommend a patch test before regular use.

What Makes Peptide Fusion a Good Peptide Cream For Face Care?

Rather than relying on hydration alone, Peptide Fusion pairs a studied biomimetic peptide with multi-depth hyaluronic acid and antioxidant-rich Ginkgo Biloba, so it’s formulated to support your skin’s own renewal processes, not just moisturize on top of them.

Can I Use Peptide Fusion Long-Term?

Yes. Peptide Fusion is formulated for consistent, long-term use. Early research on its key peptide shows measurable changes within a few weeks, though lasting results come from consistent, daily use over time.

Can I Use Peptide Fusion If I Don’t Experience Menopause?

Absolutely. Peptide Fusion’s peptide and hydration complex is beneficial for anyone noticing early signs of fine lines or a loss of resilience, regardless of age.

Can Men Use Peptide Fusion?

Yes. Peptide Fusion is suitable for both men and women.

Can I Use Peptide Fusion If I Have a Medical or Skin Condition?

While Peptide Fusion is formulated to be gentle and suitable for all skin types, we recommend consulting a healthcare professional or dermatologist if you have specific medical or skin conditions.

How Can I Order Peptide Fusion Right Now?

Click the button on this page to go to our secure order page. Peptide Fusion starts at $37.8 per bottle with Subscribe & Save.

Will I Be Able to Track My Order Once It’s Been Placed?

Absolutely. Once your order is processed, you’ll receive a confirmation email with tracking details. Our Customer Service team is available 24/7 at (800) 595-0735 (US toll-free) or +1-703-740-4444 (international).

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